Author

Michal J. Nagiec

Weill Cornell MedicineORCID 0009-0005-1390-8573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Eric E. GardneriD· 3 shared John BlenisiD· 3 shared Bobak ParangiD· 2 shared Nikos KoundourosiD· 2 shared Rabia Khan· 2 shared Anders Peter MutveiiD· 1 shared Andre Chavez· 1 shared Antonino MontalbanoiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

Eric E. GardnerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 15, 2025

Propionate metabolism dysregulation promotes drug-tolerant persister cell survival in non-small cell lung cancer

Bobak Parang, Liron Yoffe, Rabia Khan…·John Blenis

This study shows that propionate metabolism dysregulation, through MMA accumulation and EMT activation, promotes drug-tolerant persister cell survival in NSCLC.

DOI 10.1101/2025.10.15.682658

humanmetabolomics

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Cell BiologybioRxivPreprintSep 22, 2025

Lysosome-dependent nutrient scavenging underliesstress adaptation during epithelial-to-mesenchymaltransition

Michal J. Nagiec, Paola M. Cavaliere, Friederike Dündar…·John Blenis

This study shows that invasive cancer cells use lysosome-mediated nutrient scavenging during EMT, bypassing plasma membrane transport, and that this process is regulated by c-MYC downregulation.

DOI 10.1101/2025.09.22.677807

humanbulk RNA-seq

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Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedMay 14, 2024

LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase

John R. Ferrarone, Jerin Thomas, Arun M. Unni…·HAROLD E. VARMUS

This study identifies LKB1's role in suppressing growth by activating PIKFYVE to promote EGFR internalization in LUAD.

11 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky