Alena Kroupova

This study determines the atomic structure of the human tRNA-ligase complex and reveals its assembly mechanism and functional implications.

This paper introduces a method called cerebody to detect and enrich endogenous cereblon substrates by targeting C-terminal cyclic imide modifications.

The paper introduces CRBNmidi, a Cereblon construct that enables high-resolution structural and biophysical studies of degraders without requiring DDB1 co-expression.