Sude Beşkardeş

The paper investigates how cellular and epigenetic contexts influence Neurog2 binding and its functional consequences in mouse embryonic stem cells and neural progenitor cells, revealing cell-type-specific chromatin accessibility and interactors.

This study identifies innate immune memory after brain injury as a driver of chronic cardiac dysfunction, showing that post-stroke epigenetic changes in myeloid cells lead to inflammation and fibrosis in the heart.