Olga I. Kubrak

The paper identifies HR3/RORα as a conserved cholesterol sensor that activates the TOR pathway in Drosophila and human cells, linking cholesterol availability to growth regulation.

This study identifies gut hormone signaling as a driver of sex differences in metabolism and behavior in Drosophila, revealing conserved mechanisms across species.

This study identifies saITP and Gyc76C as key regulators of water balance in Drosophila hindgut via a neuroendocrine axis.

The paper introduces ClimbMaster, an automated platform to assess exercise-induced adaptations in Drosophila, showing exercise improves endurance, fat loss, and insulin sensitivity, and rapamycin mitigates age-related decline.

The paper shows that cytokine signaling from the Drosophila gut to brain glial cells regulates sleep, with oxidative stress-induced cytokines promoting sleep during intestinal inflammation.

The paper identifies a muscle-neuronal-fat tissue axis that modulates insulin secretion and adipocyte sensitivity to high-sugar diets, preventing hyperglycemia.