Author

David F. LePage

Case Western Reserve UniversityORCID 0009-0008-3820-0645Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Ronald A. ConloniD· 2 shared Adam Swayze· 1 shared Artur S. Gevorgyan· 1 shared Baraa S. Nawash· 1 shared Berit E. PowersiD· 1 shared Daniela SchlatzeriD· 1 shared Elizabeth A. KnaussiD· 1 shared Frank RigoiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

Ronald A. ConlonORCID

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2 papers

Recent·Most cited

PhysiologyJournal of Thrombosis and HaemostasisPeer-reviewedMar 18, 2024

A Mouse Model of the Protease Activated Receptor 4 (PAR4) Pro310Leu Variant has Reduced Platelet Reactivity

Han Xu, Elizabeth A. Knauss, Maria de la Fuente…·Marvin T. Nieman

This study creates a mouse model of the PAR4-P310L variant and shows reduced platelet reactivity to PAR4-activation peptide and thrombin, with no effect on ADP and convulxin responses.

12 citations

mouseflow cytometry

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NeuroscienceNaturePeer-reviewedJul 1, 2020

Therapeutic suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease in mice

Matthew S. Elitt, Lilianne Barbar, H. Elizabeth Shick…·Paul J. Tesar

This paper shows that reducing PLP1 expression in a mouse model of PMD improves myelination, motor function, and lifespan, supporting PLP1 suppression as a therapeutic strategy.

75 citationstop 2%

mouseexperimental assay

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