Rosana Castro-Mecinas

This study shows that activating HIF2 causes vascular remodeling, inflammation, and coronary issues similar to Kawasaki disease, using a new mouse model and human tissue analysis.

This study shows that HIF2 signaling in the Wt1 lineage prevents cardiomegaly and pulmonary remodeling during chronic hypoxia but causes microvascular instability and cardiac dysfunction when absent.