Circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, India
Silvia ArgimóniD, Geetha NagarajiD, Varun ShamannaiD, Dharmavaram SravaniiD, Ashwini Kodlipet Vasanth, Akshatha PrasannaiD, Aruna Ananda PoojaryiD, Anurag Kumar BariiD, Anthony P. UnderwoodiD, Mihir Kekre, Stephen G. BakeriD, David M. AanenseniD, Ravikumar Kadahalli LingegowdaiD
Abstract
We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene blaSHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance.
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