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Synthetic BiologyScientific Reports
Peer-reviewed journal article

Demonstration of End-to-End Automation of DNA Data Storage

Christopher N. TakahashiiD, Bichlien H. NguyeniD, Karin StraußiD, Luís CezeiD

Abstract

We developed a complete end-to-end DNA data storage device. The device enables the encoding of data, which is then written to a DNA oligonucleotide using a custom DNA synthesizer, pooled for liquid storage, and read using a nanopore sequencer and a novel, minimal preparation protocol. We demonstrate an automated 5-byte write, store, and read cycle with the ability to expand as new technology is available.

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