electrophysiology

The paper introduces two free LabView-based software tools for ion flux measurements using Scanning Ion-Selective Electrodes (SISE).

The paper investigates MT electrical oscillations in the hippocampus and neocortex of adult rats, finding region-specific frequency peaks and amplitude differences.

This study shows sustained visual signals in the primate cerebellar dentate nucleus are involved in visuomotor associative learning by enhancing discrimination of visual objects based on saccade direction.

This study shows TRPM7 is essential for human CD4 T-cell activation and differentiation through Mg2+ dependent Ca2+ signaling and NFAT translocation.

This study uses MEG and eye-tracking to show that active vision modulates early cortical visual processing through sequential modulations across saccades, beyond adaptation effects.

This study examines corticospinal excitability during mediolateral gait instability and finds increased excitability in upper-leg muscles but not lower-leg muscles during destabilized treadmill walking.

The paper develops and validates a multiscale cortical circuit model to simulate TMS-evoked responses, revealing mechanisms of cortical activation and inhibition.

This study investigates the inhibitory effects of bisphosphonates on Thermotoga maritima mPPase, revealing conformational asymmetry and symmetry-breaking during catalysis.

The paper measures ERGs in mice to assess contributions of rod, RPE, and Müller glial cells to dark and light-driven changes in sub-retinal space ion concentrations.

This paper develops a wireless bioelectronic actuator for wound healing in pigs, showing reduced M1/M2 macrophage ratio and increased re-epithelialization in treated wounds.

The paper shows that inhibitory neurons can suppress excess synchrony caused by over-represented excitatory di-synaptic motifs in neural networks.

This study evaluates GRU and LSTM for seizure detection in animal EEG data from rats exposed to kainate or Soman, showing better performance than classical models.

This paper develops a coreactant-free ECL sensing platform with entwined spiral microelectrodes for sensitive, multiplexed POC diagnostics.

This paper introduces a biodegradable ECoG array with high electrode density and fidelity, demonstrating its ability to map cortical seizures and classify seizure stages with high accuracy in vivo.

This paper develops an optimized inkjet-printed OECT platform with high transconductance and fast response times, demonstrating biosensing and neural recording capabilities in a rat model.

The paper correlates rate of torque development with corticospinal excitability during explosive contractions and finds MEP remains constant while silent period duration increases.

This study identifies LPHN2 as a force-sensing GPCR critical for auditory function, showing its role in mechanoelectrical transduction and hearing loss when deficient.

This paper develops a zwitterionic hydrogel-based double-network design for PEDOT:PSS that suppresses the foreign body response by 64% and improves conductivity by over one order of magnitude.

The paper identifies a conserved voltage-dependent pacemaker current essential for slow firing in neurons and cardiac cells, confirmed by models and experiments.

This paper introduces a multilayered nanomembrane platform for stretchable metal electronics, achieving high conductivity at extreme strains through crack-bridging pathways.

This paper introduces a graphene-based probe for high-density, long-term neuronal recording at neuronal density, demonstrating reliable signal capture and connectivity analysis in vivo.

This study shows adenosine and low oxygen reduce bladder contractility via A2B receptors and BKCa channels in mice.

This study modifies a computational model of hiPSC-CMs to compare their excitation properties with hV-CMs under various conditions and finds hiPSC-CMs are more excitable due to their depolarized resting potential and intrinsic automaticity.

This study compares temperature sensitivity of TRPM2 channels in zebrafish and human, finding that human TRPM2 gating evolved to be temperature dependent while inactivation was already temperature sensitive in early vertebrates.

This study investigates how missense mutations in the CTD of Nav1.5 affect gating properties, revealing distinct effects on inactivation and activation.

This study examines hERG1NP variants linked to sudden death, finding some reduce and others increase hERG1NP activity through different mechanisms.

This paper introduces FlexEGG, a flexible electronic system for high-fidelity electrogastrography monitoring, demonstrating its potential for continuous gastrointestinal electrophysiology tracking in real-world settings.

This study shows that combining CFTR modulators with amphotericin B increases HCO3- secretion and airway surface liquid pH in CF airway epithelia more than either treatment alone.

This paper introduces a wearable patch for non-invasive ultrasound neuromodulation and sleep recording, showing increased REM sleep duration and reduced latency in human subjects.