Hydrogels: synthesis, properties, applications

This paper develops self-healing hydrogels to support choroidal endothelial cell transplantation in a rat model, showing improved cell retention compared to cell suspensions.

This study uses engineered 3D hydrogels to generate placental organoids and shows they support trophoblast viability and differentiation comparable to Matrigel.

This study develops a 3D in vitro model of cervical dysplasia to evaluate the efficacy of EC-ethanol injection for treating cervical dysplasia ablation.

The paper develops a cell culture insert model with hydrogels to study transplacental transport by incorporating stromal properties.

The paper optimizes the composition of a polyurethane/gelatin hydrogel system for protein imprinting by varying monomer, crosslinker, and gelatin concentrations to maximize adsorption capacity and imprinting efficiency.

This paper develops a 3D multilayer multicellular hydrogel model of endometrial cancer for drug screening and treatment development, showing improved microvessel formation and cancer invasion compared to Matrigel.

This study evaluates the skin irritation potential of a domestic hydrogel using intradermal injections in rabbits, finding no irritation response.

The paper measures thermal properties of agarose hydrogels and compares them to articular cartilage, finding similar thermal characteristics.

This study shows that reducing reactive oxygen species and increasing hydrogel porosity improves cell viability and function in photocrosslinked gelatin-thiol hydrogels.

This study compares mechanical testing techniques for soft gels, highlighting the importance of time and spatial scales in characterizing biomaterials.

The paper develops a computational model to simulate a two-component hydrogel system's behavior and assesses its impact on cell growth for tissue regeneration.

This study develops thermo-responsive hydrogels that target inflamed colon mucosa for IBD treatment by exploiting charge-mediated interactions and thermo-responsiveness.

PenTag enables specific, covalent conjugation of proteins to ligands for biohybrid material synthesis, demonstrating applications in hydrogels and computational systems.

This study develops covalent alginate hydrogels using SPAAC cross-linking for encapsulating human adipose MSCs, demonstrating their viability and immunomodulatory activity in vitro.

The paper develops a computational method to study how mechanical stress affects enzyme-catalyzed reactions with complex kinetics.

This paper develops a red light-responsive hydrogel that allows reversible control of stiffness for cell positioning in microfluidic systems.

The paper develops a material-genetic interface as a safety switch for engineered cells in hydrogels to control therapeutic agent production based on the presence of the embedding material.

This paper develops a hydrogel-based containment system for genetically modified microorganisms to enable safe, retrievable, and functional biosensing applications.

This study investigates CNS foreign body responses (FBRs) and shows they mimic wound responses, altering biomaterial functions based on interface properties.

This paper introduces a living material platform that traps engineered E. coli in hydrogels using adhesin-mediated anchoring, reducing bacterial leakage and enabling controlled release of antimicrobial proteins.

This paper demonstrates genetic control of radical crosslinking in a hydrogel using extracellular electron transfer from Shewanella oneidensis, showing that bacterial genetics influence hydrogel properties like stiffness and crosslinking rate.

The paper demonstrates the use of cell-free genetic devices in hydrogels to create autonomic and adaptive materials that respond to external stimuli.

This study shows that non-adhesive alginate hydrogels support the growth and differentiation of human intestinal organoids, comparable to Matrigel.