Forensic and Genetic Research

This paper uses a deep learning approach to analyze whole-genome sequences and supports the back to Africa model over other hypotheses about human migration.

Ohana detects selection in multiple populations by modeling ancestral admixture components, identifying loci with extreme genetic differentiation and new candidate regions in admixed populations.

This study explores using deep convolutional neural networks to classify human populations based on SNP image graphs from genome-wide data, achieving high accuracy in some cases.

The paper introduces two selection statistics for detecting selection signals in low-coverage sequencing data using PCAngsd, showing they control false positives and match results from high-quality genotypes.

ARCHes infers ancestry composition using haplotype-based models, outperforming RFMix in global and local ancestry assignment across diverse populations.

The paper analyzes ancient genomes from Tiwanaku to show genetic homogeneity in the Lake Titicaca Basin over 1200 years but genetic diversity in ritual core individuals, suggesting foreign influence.

The paper uses whole-genome sequencing to analyze indigenous ancestry in Uruguayans, identifying Amerindian genetic heritage and estimating admixture timing.

This paper improves BGA inference methods to account for recent admixture, showing improved accuracy and a likelihood ratio test for detecting recent admixture in genotype data.

This paper compares two likelihood ratio systems using the PROVEDIt dataset to evaluate their discrimination performance and LR value differences.

The paper genotypes 22 STR markers from 1000 Genomes Project data using HipSTR, creating an open-access database showing reliable allele frequencies and population separation.

This paper uses modern and ancient genome-wide data to infer multiple waves of admixture and the peopling of the Tibet Plateau, identifying genetic connections and population stratifications among Tibetans and East Asians.

The paper models ancestry in Arabians and Iranians, finding strong west-east population structure and evidence linking east Arabians to basal Eurasians.

AFA estimates ancestral allele frequencies in admixed populations with high accuracy, showing strong correlation with gnomAD frequencies in the Hispanic Community Health Study/Study of Latinos.

This study analyzes 137 Middle Eastern genomes to reveal population history, ancestry, and selection patterns, showing no out-of-Africa expansions but elevated Basal Eurasian ancestry in Arabians.

The paper curates a dataset of 34 high-coverage shotgun human genomes, including ancient and modern samples, along with the genetic pipeline used for processing.

This study connects genetic ancestry from three ancient populations to complex traits in Estonian Biobank samples, finding ancestry-specific contributions to traits like BMI and blood cholesterol.

This paper shows that combining ancient DNA and radiocarbon dating can narrow date ranges for related individuals by incorporating biological constraints on death age separations.

This study introduces a Y-chromosome capture assay (YMCA) to improve NRY coverage and haplogroup resolution, revealing new evidence for a two-path Neolithic expansion to Western Europe.

This study analyzes genome-wide SNP data from 510 individuals across 38 Mongolic, Tungusic, and Sinitic populations to explore genetic structure, admixture history, and demographic patterns in North-East Asia.

This paper models the impact of climate and terrain on human ancestral genetic lineages, showing that these factors explain lineage divergence and migration patterns.

The paper retrieves and analyzes low-coverage mammalian ancient genomes from 25,000-year-old sediments, revealing new insights into the genetic history of humans, wolves, and bison.

This paper presents the first dataset of clinically relevant gene variants in the Serbian population, identifying unique genetic determinants and their potential health impacts.

This study shows inbreeding frequency decreased over time in ancient Eurasian populations, linked to population growth from agricultural practices.

The paper reports the whole genome sequencing of a 1600-year-old mummified sheep from a salt mine, showing exceptional DNA preservation and linking it to modern Southwest Asian breeds.

This study integrates isotopic and genomic data from Tell Atchana to examine human mobility during the 2nd millennium BC, finding limited individual mobility despite high regional interaction.

The paper identifies shared post-admixture adaptation patterns in the Americas by analyzing genomic data from 6,000 admixed individuals, highlighting regions associated with immune response and disease traits.

The paper evaluates the coverage of a probabilistic genotyping system by testing multiple layers of conservativism and finds improved precision with extended MCMC runs.

The paper tests two methods for quantifying Monte Carlo variation in probabilistic genotyping, finding both fall short of achieving 99% coverage but provide additional conservatism.

The paper reconstructs the demographic history of Tai-Kadai and Sinitic people in South China using genome-wide data and reference datasets, revealing genetic contributions from millet and rice farmers.

This study analyzes genomic data to determine the origin and genetic structure of Chinese Hui people, finding strong East Asian affinity and supporting a cultural diffusion model over demic diffusion.