Forensic and Genetic Research

This paper introduces methods to infer population histories using ancient genomes and genealogies, revealing insights into population dynamics and mutation rates in ancient populations.

The paper identifies significant Central Asian ancestry in Bulgarians and early medieval populations, linking it to the Wusun tribes and suggesting historical migration patterns.

The paper shows that cousin marriage preferences increase long runs of homozygosity (ROH) in global populations by 1.5 times, but marriage practices explain only a small portion of ROH variation.

This study analyzes the genetic structure of Gullah African Americans, finding higher African ancestry and lower European admixture compared to non-Gullah African Americans.

This study examines the genetic structure of the Norwegian population, identifying two distinct genetic regions and highlighting the impact of geography on migration patterns and ancestry.

This study uses genome-wide SNP data from 33 ethnolinguistic groups in Thailand and Laos to reconstruct the genetic history of Mainland Southeast Asia, revealing language-based genetic structure and admixture events.

DamageProfiler is a Java-based tool for analyzing damage patterns in ancient DNA, providing user-friendly interfaces and output formats for integration into analysis pipelines.

The paper presents genomic data from a Late Epigravettian individual in Italy dated to 16,980-16,510 cal BP, showing genetic replacement associated with the emergence of Late Epigravettian culture, pushing back the spread of a Balkan/Anatolian genetic component by 3,000 years.

This study characterizes the forensic genetic polymorphism of Hainan Li population using MPS-based DNA profiling and establishes population genetic datasets for further analysis.

The paper shows PCA results in population genetics are unreliable and can be manipulated, suggesting a need for alternative methods.

This study investigates genetic substructure and demographic history of South African Bantu speakers using genome-wide data, revealing fine-scale population structure aligned with geography and linguistics.

The paper recalculates divergence times between populations using SNPs from the 1000 Genomes Project by comparing individuals to an out-group.

The paper develops a Bayesian logistic regression framework with sensitivity analysis to model DNA transfer and persistence on skin surfaces, incorporating multiple contacts and background DNA.

The paper analyzes genomic data from Indigenous groups in Panama to reveal pre-Hispanic demographic changes and the genetic structure of the Isthmo-Colombian area.

This study identifies high genetic heterogeneity in the Kuwaiti population by analyzing genome-wide SNP data from 583 individuals, revealing distinct subgroups with different ancestral origins.

The paper generates the first complete mitochondrial reference genome for Zoroastrian-Parsis, identifies genetic variants, and links them to longevity and disease, while highlighting the impact of endogamy and non-smoking culture on mutational signatures.

The paper analyzes mitochondrial genome variation across human populations to identify co-mutation patterns and epistatic interactions, finding subpopulation-specific biases in mutation clustering.

The paper infers genealogical history and social behaviors from IBD segments in UK Biobank data, revealing population-scale genetic connections and regional family preferences.

The paper re-evaluates binomial inference for SNP-based forensic mixtures, introducing NITZq to calculate likelihood ratios and comparing it to EUROFORMIX.

The paper presents genomic analyses of 10,376 Chinese individuals, identifying novel genetic variations and providing a reference haplotype map, along with an imputation server for improved accuracy.

The paper evaluates an ancestry panel using 165 SNPs in three southern Chinese populations, showing improved forensic performance over STR-based systems but limitations in intercontinental ancestry inference.

The paper examines how mutation, recombination, selection, and demography shape genetic variation across different regions of the human X chromosome using data from 26 populations.

The paper analyzes mitochondrial genome diversity in the Central Siberian Plateau to trace genetic connections between the Yenisei-Sayan region and Northeast Eurasia over the last 10,000 years.

The paper analyzes maternal lineages from 10-11th century commoner cemeteries in the Carpathian Basin, finding they differ from elites and show admixture with eastern immigrant groups.

This paper introduces two methods for estimating divergence times from DNA sequences using coalescent theory and demonstrates their robustness to demographic complexities.

This paper introduces Ancestry Composition, a pipeline for ancestry deconvolution that uses over 14,000 reference haplotypes to improve accuracy and scalability.

The paper tests the use of the dog genome for sex identification in ancient pinnipeds by analyzing X chromosome read ratios and applies it to archaeological samples.

This paper develops an ABC framework to reconstruct complex admixture histories using simulated genetic data and applies it to African American and Barbadian populations.

This study examines the genetic structure of Ethiopians, linking cultural and geographic factors to genetic diversity and intermixing across 68 ethnic groups.

EMU accurately infers population structure from ultra-low coverage sequencing data with missingness, outperforming existing methods on real and simulated datasets.