Sleep and Wakefulness Research

This study examines functional connectivity in rats during the wake-sleep cycle to determine if consciousness fluctuates within brain states.

This study investigates the effects of Centella asiatica extract on sleep patterns in aged mice, finding sex-dependent improvements in sleep quantity and quality.

This study shows that sleep deprivation disrupts prefrontal inhibition of memory retrieval, linking sleep loss to intrusive memories through impaired neural circuits.

This study differentiates phasic and tonic REM sleep states using aperiodic neural activity slopes, showing phasic states have steeper low-band and flatter high-band slopes, and EM amplitudes correlate with these slopes.

This study shows that longer interstimulus intervals in automated up-phase-targeted auditory stimulation improve overnight procedural memory consolidation by enhancing K-complexes and spindle coupling.

This paper uses phylogenomics to identify sleep-related genes in Lokiarchaeota, suggesting a conserved role for sleep in cellular maintenance and organismal fitness.

This study shows that LPS-induced sepsis disrupts brain activity patterns in specific brain regions and vigilance states, with early changes in sleep-wake dynamics preceding spectral alterations.

This study examines SWA dynamics during mouse awakening from anesthesia, showing state-dependent changes in spectral power and propagation patterns across brain regions.

This study examines EEG spectral power dynamics across sleep stages and their associations with sleep quality and aging, revealing novel relationships between frequency bands and sleep metrics.

The paper examines the association between objective sleep efficiency and hippocampal subfield volumes in older adults, finding a positive link with entorhinal cortex volume and better memory performance.

This study investigates how different somatosensory stimulations affect dream incorporation, finding no significant difference between stimulation and sham conditions.

This study investigates how chronic short sleep affects metabolism and survival under oxidative stress in mutants, finding common metabolic defects and suggesting lipid metabolism issues may underlie oxidative stress sensitivity.

The paper examines how REM sleep disruption and vagal activity during REM predict extinction memory in trauma-exposed individuals, finding that both factors are linked to poorer memory outcomes.

This study finds that slow oscillation-spindle coupling during sleep predicts better sequence-based language learning and is linked to memory consolidation and theta activity.

This study shows HSF1 regulates sleep-wake cycles in mice and Drosophila by affecting synaptic organization and sleep-related gene expression.

This study shows that visual training increases fast sleep spindle density and clustering in young adults, with no age-related differences.

The paper demonstrates that mCLAS adaptively rescues disease-specific sleep and wake phenotypes in AD and PD mouse models.

The paper examines sleep spindle activity and memory consolidation in early psychosis patients and their relatives, finding spindle deficits and memory issues in patients but not relatives.

The paper identifies PKA and phosphatases as regulators of sleep-wake cycles through genetic and functional studies in mice.

This study identifies conserved sleep-related gene orthologs in Chlamydomonas reinhardtii, suggesting evolutionary continuity of sleep functions across species.

This study shows that sleep disruption improves performance in visual and olfactory decision-making tasks in larval zebrafish by increasing reaction times and correct decisions.

This study investigates whether REM sleep facilitates hippocampal memory differentiation after prediction errors, finding greater differentiation in REM sleep conditions in specific hippocampal regions.

This study identifies heightened LC-NE neuron activity and altered connectivity as causes of sleep fragmentation and memory deficits in a 16p11.2 deletion ASD mouse model.

This study examines the effects of sleep deprivation on synaptic vulnerability across developmental stages in mice, finding heightened sensitivity in juveniles and links to ASD risk.

The paper uses a mathematical model to analyze sleep patterns in infants and young children, finding developmental changes in sleep homeostasis and circadian rhythms.

The paper analyzes OXR1 and OXR2 mRNA expression in the dorsal hippocampus and related brain regions using RNAscope in situ hybridization, revealing distinct expression patterns and cell-type specificity.

The paper examines local sleep states in zebra finches, finding that sleep stages vary across different regions of the avian pallium, challenging the idea of global sleep states.

This study identifies a hypothalamic circuit involving CRHPVN neurons that mediates stress-induced impairments in memory and sleep.

The paper records claustrum neurons during human sleep and finds they increase activity and track slow waves during NREM sleep.

This study investigates how tapeworm infection affects sleep behavior in three-spined sticklebacks, finding altered sleep patterns at different timepoints post-exposure.