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This study evaluates the clinical value of conductive cardiac patches by testing different conductivities and shows that higher conductivity reduces arrhythmia risks in post-MI hearts.

This study shows Fc-silencing mutations in therapeutic antibodies do not block FCRL5 binding, potentially affecting B cell function through novel Fc-FCRL5 interactions.

This study links neuronal cell loss and gliosis in hippocampal sclerosis to tissue stiffness using mechanical testing and deep learning analysis of histopathology.

This study compares immune responses to microporous annealed particle scaffolds and nanoporous hydrogels, finding that MAP scaffolds reduce foreign body response by suppressing complement-fibroblast-macrophage signaling.

This paper validates a CUBIC-based workflow for volumetric analysis of follicles and vasculature in human ovarian tissue, showing comparable follicle density to histology and detailed vascular morphometrics.

This study shows that noncoaxial transcatheter aortic valve deployment creates cusp-specific thrombogenic microenvironments by altering sinus hemodynamics, leading to localized leaflet thrombus formation.

This study investigates how lipid tail length in peptide amphiphile nanostructures affects their interactions with biological systems, showing that molecular design can control biointeractions and tumor accumulation.

This paper develops a 3D in vitro model of the human hepatobiliary junction that recapitulates bile flow and dysfunction under hypoxia-reoxygenation, offering insights into biliary pathophysiology.

The paper analyzes how cell shape correlates with proteomic features across multiple cell lines using image-based spatial proteomics data.

This study demonstrates the use of in vivo prime editing to correct a cardiomyopathy-causing mutation in a humanized mouse model, rescuing disease phenotypes.

HYPER-Net enables physics-conditioned self-supervised reconstruction for Fourier light-field microscopy, improving volumetric imaging across diverse biological contexts.

This paper introduces E-cardiac, a biosensor that monitors oxidative stress in beating hearts with mechanical adaptation, distinguishing ischemia-reperfusion injury severity and detecting the ECG blind window.

This study develops a modified self-amplifying RNA-based BiTE system that provides long-term B cell clearance with a single injection.

This paper introduces a membrane-free alveoli-on-a-chip using biodegradable scaffolds that mimics interstitial mechanics, immune trafficking, and aerosolized mRNA delivery in human alveoli.

This paper introduces REVi-SCOPE, a platform that rapidly characterizes cardiac variants' functional impact, enabling precision cardiology by analyzing VUSs in 10 days.

This study shows that modifying ionizable lipids and formulation parameters of mRNA vaccines can enhance CD4+ T cell immunity and improve vaccine efficacy.

The paper evaluates a laparoscopic fluorescence imaging platform to quantify light-triggered drug release in cancer models, showing strong correlation with standard measurements and potential for guided treatment.

The paper adapts a two-photon microscope to detect both visible and near-infrared fluorescence, enabling simultaneous dopamine and calcium imaging in the retina.

This paper develops a method to grow engineered liver tissue in vivo by using synthetic biology to trigger on-demand expansion after implantation.

This review evaluates ML applications for MALDI-TOF MS in clinical microbiology, identifying trends and challenges in bacterial identification, resistance prediction, and strain typing.