Author

A. A. Exner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:imaging· 5 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Organism:rat· 2

Frequent Co-Authors

D. Wegierak· 3 shared E. C. Abenojar· 3 shared M. B. Cooley· 3 shared M. C. Kolios· 3 shared C. Hernandez· 2 shared E. Abenojar· 2 shared F. M. Berg· 2 shared J. P. Basilion· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioengineering

D. Wegierak

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Decorrelation Time Mapping as an Analysis Tool for Nanobubble-Based Contrast Enhanced Ultrasound Imaging

D. Wegierak, M. B. Cooley, R. Perera, W. J. Wultange, U. Gurkan, M. C. Kolios, A. A. Exner

This paper introduces decorrelation time mapping to distinguish intravascular and extravascular nanobubble signals in ultrasound imaging, showing higher decorrelation times in tumor tissue compared to normal tissue.

IEEE Transactions on Medical Imaging · Jun 1, 2024Peer-reviewedBioengineering

Assessing Tumor Microenvironment Characteristics and Stratifying EPR with a Nanobubble Companion Nanoparticle via Contrast-Enhanced Ultrasound Imaging

M. B. Cooley, D. Wegierak, R. Perera, E. C. Abenojar, P. A. Nittayacharn, F. M. Berg, Y. Kim, M. C. Kolios, A. A. Exner

This paper uses contrast-enhanced ultrasound imaging with nanobubbles to assess tumor microenvironment characteristics and predict nanoparticle distribution in tumors with different vascular permeability.

bioRxiv · Nov 20, 2023 · PreprintBioengineering

Ultrasound-Mediated Drug-free Theranostics for Treatment of Prostate Cancer

R. H. Perera, F. M. Berg, E. C. Abenojar, P. Nittayacharn, Y. Kim, X. Wang, J. P. Basilion, A. A. Exner

This paper demonstrates that PSMA-targeted nanobubbles combined with ultrasound treatment selectively induce apoptosis in PSMA-expressing prostate cancer tumors in animal models.

bioRxiv · Sep 13, 2023Bioengineering

Conventional polymers may unintentionally refill in vivo with unassociated drugs

K. Young, A. B. Dogan, C. Hernandez, A. A. Exner, H. A. von Recum

This paper investigates the refilling capacity of PLGA implants, finding that even unmodified PLGA can refill with unassociated drugs, contrary to expectations.

bioRxiv · Mar 21, 2022 · PreprintBioengineering

Characterization of the Interaction of Nanobubble Ultrasound Contrast Agents with Human Blood Components

M. B. Cooley, E. C. Abenojar, D. Wegierak, A. Sen Gupta, M. C. Kolios, A. A. Exner

This paper examines how nanobubbles interact with human blood components, finding that nanobubbles in whole blood show increased signal enhancement over time compared to other solutions.

bioRxiv · Feb 11, 2022Bioengineering

Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis and beta-cell mass decline in mouse models of type 1 diabetes

D. G. Ramirez, E. Abenojar, C. Hernandez, L. A. Papazian, S. Passman, V. Pham, A. A. Exner, R. K. K. Benninger

bioRxiv · Dec 20, 2019Bioengineering

Real Time Ultrasound Molecular Imaging of Prostate Cancer with PSMA-targeted Nanobubbles

R. H. Perera, A. De Leon, X. Wang, Y. Wang, G. Ramamurthy, P. Peiris, E. Abenojar, J. P. Basilion, A. A. Exner

This study develops PSMA-targeted nanobubbles for real-time ultrasound imaging of prostate cancer in mice, showing improved tumor detection and retention.

bioRxiv · May 10, 2019Bioengineering