Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
S. Haupt, N. Gleim, A. Ahadova…·V. Heuveline
This paper develops a computational model to simulate colonic crypt evolution in Lynch syndrome, showing the importance of stem cell dynamics and MMR deficiency in CRC development.
S. Haupt, A. Zeilmann, A. Ahadova…·V. Heuveline
This paper develops a dynamical system model with Kronecker structure to simulate colorectal carcinogenesis pathways in Lynch syndrome, enabling mathematical analysis of tumor evolution and mutation dynamics.
A. Ballhausen, M. J. Przybilla, M. Jendrusch…·M. Kloor
The study identifies shared immunogenic neoantigens in MSI cancers and finds a negative correlation between indel mutation frequency and neoantigen immunogenicity, suggesting immunoediting during tumor evolution.