Author

A. Blum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Sanecka-Duin· 2 shared B. Krol-Jozaga· 2 shared J. Kaczmarczyk· 2 shared M. Jasinski· 2 shared P. Skoczylas· 2 shared V. Murcia Pienkowski· 2 shared A. J. McCann· 1 shared B. Zaghla· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Sanecka-Duin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of tumor-specific MHC ligands through improved biochemical isolation and incorporation of machine learning

S. Mecklenbräuker, P. Skoczylas, P. Biernat, B. Zaghla, B. Krol-Jozaga, M. Jasinski, V. Murcia Pienkowski, A. Sanecka-Duin, O. Popp, R. Szatanek, P. Mertins, J. Kaczmarczyk, A. Blum, M. G. Klatt

This paper improves the isolation of tumor-specific MHC ligands through hydrophobicity and post-translational modification considerations and introduces a machine learning model for predicting MHC ligand presentation.

bioRxiv · Jun 8, 2023 · PreprintImmunology

ARDitox: platform for the prediction of TCRs potential off-target binding

V. Murcia Pienkowski, T. Boschert, P. Skoczylas, A. Sanecka-Duin, M. Jasinski, B. Krol-Jozaga, G. Mazzocco, S. Stachura, L. Bunse, J. Kaczmarczyk, E. W. Green, A. Blum

ARDitox predicts TCR off-target binding using computational immunology and AI, identifying cross-reactive epitopes in cancer and viral targets.

bioRxiv · Apr 11, 2023 · PreprintImmunology

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.

A. J. McCann, J. Lou, M. Moustaqil, A. Blum, F. Fontaine, H. Liu, W. Luu, P. Koopman, E. Sierecki, Y. Gambin, F. A. Meunier, Z. Liu, E. Hinde, M. Francois

This study investigates how a dominant-negative SOX18 mutant disrupts transcription factor activity by interfering with chromatin-binding dynamics and recruiting the wild-type interactome.

bioRxiv · Nov 11, 2020Cell Biology