Cancer BiologybioRxivPreprint
Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis.
C.-S. Seong, C. Huang, A. C. Boese…·M. Gilbert-Ross
The paper shows that loss of HD-PTP, a tumor suppressor, promotes RAS-driven oncogenesis and is associated with adenosquamous lung cancer, suggesting it as a therapeutic target.
DOI 10.1101/2023.01.26.525772