Author

A. Chemparathy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. J. Kooistra· 1 shared A. J. Venkatakrishnan· 1 shared A. K. Ma· 1 shared B. K. Kobilka· 1 shared D. B. Lewis· 1 shared D. Endy· 1 shared D. Hilger· 1 shared G. Dhamdhere· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. J. Kooistra

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Author profile →

2 papers

Recent·Most cited

Development of CRISPR as a prophylactic strategy to combat novel coronavirus and influenza

T. R. Abbott, G. Dhamdhere, Y. Liu, X. Lin, L. E. Goudy, L. Zeng, A. Chemparathy, S. Chmura, N. Heaton, R. Debs, T. Pande, D. Endy, M. La Russa, D. B. Lewis, L. S. Qi

This paper develops a CRISPR-Cas13-based strategy called PAC-MAN to inhibit SARS-CoV-2 and influenza A virus in human cells, showing it can degrade viral sequences and reduce replication.

bioRxiv · Mar 13, 2020 · PreprintBioengineering

Uncovering patterns of atomic interactions in static and dynamic structures of proteins

A. J. Venkatakrishnan, R. Fonseca, A. K. Ma, S. A. Hollingsworth, A. Chemparathy, D. Hilger, A. J. Kooistra, R. Ahmari, M. M. Babu, B. K. Kobilka, R. Dror

The paper develops tools for analyzing interatomic interactions in protein structures and simulations, creating a web resource to identify functional interaction patterns in GPCRs, G proteins, kinases, and muscarinic receptors.

bioRxiv · Nov 13, 2019 · PreprintBiophysics