ImmunologybioRxiv
NADPH Oxidase 2 Derived Reactive Oxygen Species Promote CD8+ T cell Effector Function
J. Chen, C. Liu, A. Chernatynskaya…·C. E. Mathews
This study shows that NOX2-derived reactive oxygen species are essential for CD8+ T cell effector function by promoting T-bet expression and mTOR complex 1 activation.