Author

A. Cope

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Assay:imaging· 1

Frequent Co-Authors

A. Chandra· 1 shared B. E. Nickels· 1 shared C. Kemper· 1 shared D. M. Taylor· 1 shared D. Owen· 1 shared D. Williamson· 1 shared E. Perucha· 1 shared G. Cornish· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Chandra

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli

K. S. Skalenko, L. Li, Y. Zhang, I. O. Vvedenskaya, J. T. Winkelman, A. Cope, D. M. Taylor, P. Shah, R. H. Ebright, J. B. Kinney, Y. Zhang, B. E. Nickels

The paper identifies promoter sequence determinants and structural basis of primer-dependent transcription initiation in E. coli using MASTER and biochemical studies.

bioRxiv · Apr 6, 2021Biochemistry

Cholesterol metabolism drives regulatory B cell function

J. A. Bibby, H. A. Purvis, T. Hayday, A. Chandra, K. Okkenhaug, M. Wood, H. J. Lachmann, C. Kemper, A. Cope, E. Perucha

This study shows that cholesterol metabolism, specifically through GGPP synthesis, is essential for regulatory B cell function by promoting IL-10 production and suppressing Th1 responses.

bioRxiv · Jan 3, 2020Immunology

Differential nanoscale organisation of LFA-1 modulates T cell migration

M. Shannon, J. Pineau, J. Griffie, J. Aaron, T. Peel, D. Williamson, R. Zamoyska, A. Cope, G. Cornish, D. Owen

The paper shows that differential nanoscale organisation of LFA-1 in T-cells modulates migration speed by linking actin flow and signaling.

bioRxiv · Apr 11, 2019Immunology