Author

J. Aaron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 2 Biophysics· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Organism:human· 5 Assay:imaging· 5 Approach:microscopy & imaging analysis· 5 Approach:experimental assay· 4 Research Focus:development & morphogenesis· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

T.-L. Chew· 4 shared E. Wait· 2 shared A. Brinkworth· 1 shared A. Cope· 1 shared A. E. Palmer· 1 shared A. Ramudzuli· 1 shared A. Stubb· 1 shared A. T. Nogueira· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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4 shared papersCell Biology

T.-L. Chew

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Four-dimensional quantitative analysis of cell plate development using lattice light sheet microscopy identifies robust transition points between growth phases

R. M. Sinclair, M. Wang, M. Z. Jawaid, J. Aaron, B. Rossetti, E. Wait, K. McDonald, D. Cox, J. heddleston, T. Wilkop, G. Drakakaki

This study uses lattice light sheet microscopy to analyze cell plate development in four dimensions, identifying phase transitions and the role of callose in cytokinesis.

bioRxiv · Oct 3, 2023 · PreprintPlant Biology

Distinct mobility patterns of BRCA2 molecules at DNA damage sites

M. W. Paul, J. Aaron, E. Wait, R. M. van Genderen, A. Tyagi, H. Kabbech, I. Smal, T.-L. Chew, R. Kanaar, C. Wyman

This study quantifies BRCA2 mobility patterns at DNA damage sites using advanced microscopy, revealing immobile and subdiffusive motions that may enhance repair efficiency.

bioRxiv · Feb 20, 2023Cell Biology

Single molecule microscopy to profile the effect of zinc status of transcription factor dynamics

L. J. Damon, J. Aaron, A. E. Palmer

This study uses single molecule microscopy to investigate how zinc status affects the dynamics and DNA binding of transcription factors.

bioRxiv · May 10, 2022Biophysics

The mycobacterial mutasome: composition and recruitment in live cells

S. Gessner, Z. A.-M. Martin, M. A. Reiche, J. Santos, N. Dhar, R. Dinkele, T. J. de Wet, A. Ramudzuli, S. Anoosheh, D. M. Lang, J. Aaron, T. L. Chew, J. Herrmann, R. Mueller, J. D. McKinney, , D. F. Warner

This study identifies the molecular composition and function of the mycobacterial mutasome, showing that the ImuB-{beta} clamp interaction is essential for mutagenic DNA repair in mycobacteria.

bioRxiv · Nov 16, 2021Microbiology

Campylobacter jejuni trigger signaling through host cell focal adhesions to inhibit cell motility and impede wound repair

C. M. Klappenbach, N. M. Negretti, J. Aaron, T.-L. Chew, M. E. Konkel

This study shows that Campylobacter jejuni manipulates host cell focal adhesions to reduce motility and impair wound repair.

bioRxiv · May 14, 2021Microbiology

The Chlamydia type III effector TarP alters the dynamics and organization of host cell focal adhesions

A. T. Pedrosa, K. Murphy, A. T. Nogueira, A. Brinkworth, T. R. Thwaites, J. Aaron, T.-L. Chew, R. CARABEO

This study shows that Chlamydia's effector TarP stabilizes focal adhesions by interacting with vinculin, reducing cell motility and enhancing matrix attachment.

bioRxiv · Dec 5, 2019 · PreprintCell Biology

Differential nanoscale organisation of LFA-1 modulates T cell migration

M. Shannon, J. Pineau, J. Griffie, J. Aaron, T. Peel, D. Williamson, R. Zamoyska, A. Cope, G. Cornish, D. Owen

The paper shows that differential nanoscale organisation of LFA-1 in T-cells modulates migration speed by linking actin flow and signaling.

bioRxiv · Apr 11, 2019Immunology

Superresolution architecture of pluripotency guarding adhesions

A. Stubb, C. Guzman, E. Närvä, J. Aaron, T.-L. Chew, M. Saari, M. Miihkinen, G. Jacquemet, J. Ivaska

The paper investigates the three-dimensional architecture of unique focal adhesions in human pluripotent stem cells and identifies structural features linked to pluripotency maintenance.

bioRxiv · Sep 19, 2018 · PreprintCell Biology