BioengineeringbioRxiv
Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration
S. Herberg, D. Varghai, D. S. Alt…·E. Alsberg
This study shows that scaffold-free human mesenchymal stem cell tubes, with specific geometry and morphogen presentation, enhance endochondral bone regeneration in critical-sized femoral defects compared to loose hMSC sheets.
DOI 10.1038/s42003-020-01576-y