Author

A. D. Weems

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:human· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Approach:statistical model· 1

Frequent Co-Authors

E. S. Welf· 3 shared G. Danuser· 3 shared M. K. Driscoll· 3 shared F. Zhou· 2 shared J. Chi· 2 shared K. M. Dean· 2 shared R. P. Fiolka· 2 shared V. S. Murali· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCell Biology

E. S. Welf

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Blebs Promote Cell Survival by Assembling Oncogenic Signaling Hubs

A. D. Weems, E. S. Welf, M. K. Driscoll, F. Zhou, H. Mazloom-Farsibaf, B.-J. Chang, V. S. Murali, G. M. Gihana, B. G. Weiss, J. Chi, D. Rajendran, K. M. Dean, R. P. Fiolka, G. Danuser

This study shows blebs form signaling hubs that promote anoikis resistance in cancer cells by recruiting septins and activating ERK/PI3K pathways.

bioRxiv · Apr 23, 2021Cell Biology

Proteolysis-free cell migration through crowded environments via mechanical worrying

M. K. Driscoll, E. S. Welf, A. D. Weems, E. Sapoznik, F. Zhou, V. S. Murali, J. M. Garcia-Arcos, M. Roh-Johnson, M. Piel, K. M. Dean, R. P. Fiolka, G. Danuser

The paper shows amoeboid melanoma cells migrate through crowded environments by mechanically degrading extracellular matrix via bleb-driven abrading, without proteolysis.

bioRxiv · Nov 9, 2020 · PreprintCell Biology

A unified role for membrane-cortex detachment during cell protrusion initiation

E. S. Welf, C. E. Miles, J. Huh, M. K. Driscoll, T. Isogai, J. Noh, A. D. Weems, J. Chi, T. Pohlkamp, K. Dean, R. Fiolka, A. Mogilner, G. Danuser

The paper shows that membrane-cortex detachment is essential for initiating both pressure-based and actin-based protrusions, challenging the Brownian ratchet model and unifying protrusion regulation.

bioRxiv · Jul 9, 2019 · PreprintCell Biology