Mycobacterium tuberculosis exploits SIRT2 for iron acquisition to facilitate its intracellular survival
S. Talukdar, R. Modanwal, G. K. Chaubey, A. Dhiman, R. Dilawari, C. I. Raje, M. Raje
This study shows Mtb uses SIRT2 to acquire iron, reducing immune response and increasing survival, with implications for new host-targeted therapies.
bioRxiv · Jan 5, 2024 · PreprintCell Biology