Author

A. Echterhof

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:software / tool· 1

Frequent Co-Authors

F. G. Blankenberg· 2 shared P. Bollyky· 2 shared Q. Chen· 2 shared T. Dharmaraj· 2 shared A. Frymoyer· 1 shared A. Hargil· 1 shared C. de Leeuw· 1 shared C. E. Milla· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

F. G. Blankenberg

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo

A. Echterhof, T. Dharmaraj, R. McBride, J. D. Berry, M. Hopkins, H. Selvakumar, K.-Y. Lin, L. Chia, C.-C. Shen, W. Lioa, P. Lee, T. Yeh, G. Suh, F. G. Blankenberg, A. Frymoyer, P. Bollyky

This study examines how neutrophils affect bacteriophage clearance and pharmacokinetics in mice, finding minimal impact from neutrophils but significant inactivation of phages over time.

JCI Insight · Oct 22, 2024Peer-reviewedPharmacology & Toxicology

Dosing and Delivery of Bacteriophage Therapy In a Murine Wound Infection Model

Y.-H. Lin, T. Dharmaraj, Q. Chen, A. Echterhof, R. Manasherob, L. J. Zhang, Z. Li, C. de Leeuw, N. A. Peterson, T. H. W. Chang, W. Stannard, M. Hajfathalian, A. Hargil, H. A. Martinez, J. Pourtois, , P. L. Bollyky

This study evaluates phage therapy dosing and delivery in a mouse wound infection model, finding topical high-dose repeated administration effective and developing a sustained-release hydrogel system.

bioRxiv · May 7, 2024Bioengineering

A Blueprint for Broadly Effective Bacteriophage Therapy Against Bacterial Infections

K. M. Kim, Q. Chen, A. Echterhof, R. C. McBride, N. Pennetzdorfer, N. Banaei, E. B. Burgener, C. E. Milla, P. Bollyky

This paper develops broad-spectrum bacteriophage therapy cocktails effective against multiple bacterial strains and infections.

bioRxiv · Apr 20, 2024 · PreprintMicrobiology