Author

A. Elangovan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. M. Atkinson· 3 shared S. Oesterreich· 3 shared A. V. Lee· 2 shared J. Hooda· 2 shared K. Ding· 2 shared L. Savariau· 2 shared P. F. McAuliffe· 2 shared A. Basudan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

J. M. Atkinson

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Author profile →

3 papers

Recent·Most cited

WCRC-25: A novel luminal Invasive Lobular Carcinoma cell line model

A. Elangovan, E. A. Bossart, A. Basudan, N. Tasdemir, O. S. Shah, K. Ding, S. C. Purdy, C. Meier, T. Heim, C. Neumann, S. Attaran, L. Brown, J. Hooda, L. Miller, K. Kota, , S. Oesterreich

The paper introduces a new invasive lobular carcinoma cell line, WCRC-25, and demonstrates its molecular features and therapeutic response to PI3K/AKT inhibition.

bioRxiv · Sep 15, 2023 · PreprintCancer Biology

Loss of E-cadherin Induces IGF1R Activation Revealing a Targetable Pathway in Invasive Lobular Breast Carcinoma

A. Elangovan, J. Hooda, L. Savariau, S. Puthanmadhomnarayanan, M. E. Yates, J. Chen, D. D. Brown, P. F. McAuliffe, S. Oesterreich, J. M. Atkinson, A. V. Lee

This study shows that loss of E-cadherin in ILC leads to increased IGF1R activation and sensitivity to inhibitors, suggesting a therapeutic target and biomarker for ILC.

bioRxiv · Feb 22, 2022 · PreprintCancer Biology

Single cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells

F. Chen, K. Ding, N. Priedigkeit, A. Elangovan, K. M. Levine, N. Carleton, L. Savariau, J. M. Atkinson, S. Oesterreich, A. V. LEE

The paper uses single-cell RNA sequencing to compare transcriptional heterogeneity between invasive ductal and lobular breast cancer cell lines, identifying CDH1 loss effects and potential mediators of ILC-specific features.

bioRxiv · Feb 21, 2020Cancer Biology