Cell BiologybioRxiv
The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS-mTOR signaling and vascular function
A. F. Alghanem, C. Ta, J. M. Maurer…·R. Sah
This study shows that SWELL1 regulates endothelial AKT-eNOS and mTOR signaling, affecting vascular function and contributing to hypertension and vascular narrowing in Type 2 diabetes.
DOI 10.7554/elife.61313