Author

A. Ferguson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

A. Aggarwal· 1 shared A. Asthana· 1 shared A. Brown· 1 shared A. Fleischmann· 1 shared A. Garofoli· 1 shared A. Grey· 1 shared A. Kelleher· 1 shared A. Li· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Aggarwal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Didemnin B and ternatin-4 inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes

M. F. Juette, J. D. Carelli, E. J. Rundlet, A. Brown, S. Shao, A. Ferguson, M. R. Wasserman, M. Holm, J. Taunton, S. C. Blanchard

This study shows how didemnin B and ternatin-4 inhibit translation by trapping eEF1A in a GTPase-activated conformation using single-molecule imaging and cryo-EM.

bioRxiv · Aug 1, 2022 · PreprintBiochemistry

A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice

C. Counoupas, M. D. Johnson, A. Stella, D. H. Nguyen, A. Ferguson, A. Aggarwal, N. Bhattacharyya, A. Grey, K. Patel, R. Siddiquee, E. L. Stewart, O. Hutchings, C. Feng, N. G. G. Hansbro, U. Palendira, , J. A. Triccas

A BCG-adjuvanted vaccine provides sterilizing immunity against SARS-CoV-2 in mice, with high neutralizing antibody titers and Th1 responses.

bioRxiv · Dec 10, 2020 · PreprintMicrobiology

The Genomic Landscape of Prostate Cancer Brain Metastases

A. Rodriguez, J. Gallon, D. Akhoundova, S. Maletti, A. Ferguson, J. Cyrta, U. Amstutz, A. Garofoli, V. Paradiso, S. Tomlins, E. Hewer, V. Genitsch, A. Fleischmann, E. J. Rushing, R. Grobholz, , M. A. Rubin

This study identifies genomic alterations in prostate cancer brain metastases, highlighting mutations in NF1 and RICTOR and DNA homologous repair defects as potential drivers.

bioRxiv · May 12, 2020 · PreprintCancer Biology

Development of a Novel Class of Self-Assembling dsRNA Cancer Therapeutics: a Proof of Concept Investigation

V. Asthana, B. S. Stern, Y. Tang, P. Bugga, A. Li, A. Ferguson, A. Asthana, G. Bao, R. A. Drezek

This paper introduces a novel class of self-assembling dsRNA therapeutics that target specific oncogenic sequences and induce apoptosis in cancer cells.

bioRxiv · Apr 22, 2020Bioengineering