Author

M. D. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Aggarwal· 1 shared A. Das· 1 shared A. F. Haas· 1 shared A. Ferguson· 1 shared A. G. Patel· 1 shared A. Grey· 1 shared A. Iverson· 1 shared A. Kelleher· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Aggarwal

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.

R. H. Chapple, X. Liu, S. Natarajan, M. I. M. Alexander, Y. Kim, A. G. Patel, C. W. LaFlamme, M. Pan, W. C. Wright, H.-M. Lee, Y. Zhang, M. Lu, S. C. Koo, C. Long, J. Harper, , P. Geeleher

The paper compares mesenchymal-like gene expression programs in neuroblastoma preclinical models and patient tumors using single-cell RNA-seq and identifies chemotherapy-induced changes in PDX and GEMM.

bioRxiv · Apr 13, 2023Cancer Biology

Cryo-EM structure of the Agrobacterium tumefaciens type IV secretion system-associated T-pilus reveals stoichiometric protein-phospholipid assembly

S. Kreida, A. Narita, M. D. Johnson, E. I. Tocheva, A. Das, D. Ghosal, G. J. Jensen

The paper presents a cryo-EM structure of the Agrobacterium tumefaciens T-pilus, revealing a 1:1 stoichiometric assembly of VirB2 and phosphatidylglycerol with unique electrostatic interactions and structural features.

bioRxiv · Sep 25, 2022 · PreprintMicrobiology

Role of miR-181c in Diet-Induced Obesity Through Regulation of Lipid Synthesis in Liver

K. Akiyoshi, G. J. Boersma, M. D. Johnson, F. C. Velasquez, B. Dunkerly-Eyring, S. OBrien, A. Yamaguchi, C. Steenbergen, K. L. K. Tamashiro, S. Das

This study investigates miR-181c's role in diet-induced obesity by showing its regulation of lipid synthesis in liver and its impact on metabolic parameters.

bioRxiv · Aug 20, 2021Cell Biology

Dynamic pneumococcal genetic adaptations support bacterial growth and inflammation during coinfection with influenza

A. P. Smith, L. Lane, T. van Opijnen, S. Woolard, R. Carter, A. Iverson, C. Burnham, P. Vogel, D. Roeber, G. Hochu, M. D. Johnson, J. McCullers, J. Rosch, A. M. Smith

This study identifies bacterial genes critical for pneumococcal virulence and immune modulation during influenza coinfection using transposon mutagenesis and in vivo analysis.

bioRxiv · Jan 11, 2021Microbiology

A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice

C. Counoupas, M. D. Johnson, A. Stella, D. H. Nguyen, A. Ferguson, A. Aggarwal, N. Bhattacharyya, A. Grey, K. Patel, R. Siddiquee, E. L. Stewart, O. Hutchings, C. Feng, N. G. G. Hansbro, U. Palendira, , J. A. Triccas

A BCG-adjuvanted vaccine provides sterilizing immunity against SARS-CoV-2 in mice, with high neutralizing antibody titers and Th1 responses.

bioRxiv · Dec 10, 2020 · PreprintMicrobiology

Evidence for a biological source of widespread, reproducible nighttime oxygen spikes in tropical reef ecosystems has implications for coral health

S. K. Calhoun, A. F. Haas, Y. Takeshita, M. D. Johnson, M. D. Fox, E. L. A. Kelly, B. Mueller, M. J. A. Vermeij, L. W. Kelly, C. E. Nelson, N. N. Price, T. N. F. Roach, F. Rohwer, J. E. Smith

The paper identifies nighttime oxygen spikes in tropical reef ecosystems as a biological phenomenon linked to coral health and calcifying organisms.

bioRxiv · Mar 8, 2020 · PreprintEcology