Chimeric mRNA based COVID-19 vaccine induces protective immunity against Omicron and Delta
Q. Hu, Y. Zhao, N. Shaabani, X. Lyu, H. Sun, V. Cruz, Y. Kao, J. Xu, A. Fossier, K. Stegman, Z. Wang, Y. Hu, Y. Zheng, L. Kyaw, C. Zuluaga, , R. Chen
This study develops a chimeric mRNA vaccine that provides broad protection against Omicron and Delta variants of SARS-CoV-2 by combining RBDs from different variants.
bioRxiv · Mar 4, 2022 · PreprintImmunology