Author

A. Gopinathan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:bacteria (other)· 2 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

K. C. Huang· 3 shared C. Santangelo· 1 shared D. A. Quint· 1 shared D. K. Halladin· 1 shared D. Quint· 1 shared E. Rojas· 1 shared F. E. Ortega· 1 shared H. Shi· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersBiophysics

K. C. Huang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Synthesis, Insertion and Characterization of SARS-CoV-2 Membrane Protein Within Lipid Bilayers

Y. Zhang, S. Anbir, J. Mctiernan, S. Li, M. Worcester, P. Mishra, M. E. Colvin, A. Gopinathan, U. Mohideen, R. Zandi, T. E. Kuhlman

This study develops a method to express, purify, and insert SARS-CoV-2 M protein into lipid bilayers, characterizing its structural properties using AFM and Cryo-EM.

bioRxiv · Sep 30, 2023Biophysics

Feedback linking cell envelope stiffness, curvature, and synthesis enables robust rod-shaped bacterial growth

S. al-Mosleh, A. Gopinathan, C. Santangelo, K. C. Huang, E. Rojas

This study combines theory and experiment to show that E. coli uses feedback between cell-envelope curvature and expansion to maintain growth rate and cell width during osmotic stress.

bioRxiv · Apr 1, 2022Microbiology

Cargo-mediated mechanisms reduce inter-motor mechanical interference, promote load-sharing and enhance processivity in teams of molecular motors

N. Sarpangala, A. Gopinathan

This paper shows that cargo surface fluidity reduces mechanical interference between molecular motors, enhances load sharing, and increases processivity in motor teams through computational simulations.

bioRxiv · Jun 10, 2021 · PreprintBiophysics

Entropy-driven translocation of disordered proteins through the Gram-positive bacterial cell wall

D. K. Halladin, F. E. Ortega, K. M. Ng, M. J. Footer, N. S. Mitic, S. N. Malkov, A. Gopinathan, K. C. Huang, J. A. Theriot

The paper shows that entropy drives disordered proteins through Gram-positive bacterial cell walls, using a physical model and experimental validation.

bioRxiv · Nov 24, 2020Biophysics

Chiral twisting in cytoskeletal polymers regulates filament size and orientation

H. Shi, D. Quint, A. Gopinathan, K. C. Huang

This study shows that left-handed twisting in MreB filaments, influenced by nucleotide and membrane binding, determines filament length and orientation in Caulobacter crescentus.

bioRxiv · Nov 1, 2018Biophysics

Cargo diffusion shortens single-kinesin runs at low viscous drag

J. O. Wilson, D. A. Quint, A. Gopinathan, J. Xu

The paper uses simulations to show cargo diffusion reduces single-kinesin run length, with effects influenced by viscous drag and load direction.

bioRxiv · Aug 13, 2018Biophysics