K. C. Huang

This study uses a GFP-reporter library to profile Salmonella transcriptional dynamics during macrophage infection, revealing condition-specific regulation and novel gene activity.

This study investigates gut microbiome colonization dynamics after antibiotic use, finding prolonged delays in microbial transmission and ecological barriers to colonization.

The paper creates a mutant fitness compendium for Bifidobacterium breve to identify molecular factors affecting colonization and host-microbe interactions.

The paper shows that metabolomic rearrangements, not stress responses, control bacterial temperature adaptation, with a model explaining growth dynamics under temperature shifts.

This study shows that activating the Rcs phosphorelay in E. coli reduces growth rate and alters FtsZ distribution, with effects mediated through growth-rate changes rather than direct regulation.

This study shows that changes in bacterial cell width affect periplasmic thickness and activate the Rcs stress response system through RcsF.

This study develops a framework to distinguish resource competition from other interactions in gut bacterial communities, showing it explains most pairwise interactions and predicts community assembly.

This study combines theory and experiment to show that E. coli uses feedback between cell-envelope curvature and expansion to maintain growth rate and cell width during osmotic stress.

The paper investigates how iron and heme affect gut microbiome structure using in vitro models derived from human stool samples, showing iron deprivation reduces diversity and alters community composition.

The paper discovers novel rectangular bacterial structures in dolphin mouths and characterizes their morphology and potential bacterial origin through multiple methods.

The study identifies a strain-specific bacterial niche in the Drosophila foregut that stabilizes microbiota composition through spatial and competitive interactions.

The paper identifies conserved and non-conserved triggers of 24-nt phasiRNAs in eudicots, including new triggers and expanded loci in wild strawberry and validated pathways in rose.

This study shows that starvation causes E. coli to shrink its inner membrane and cytoplasm, driven by water loss, and that the Tol-Pal system is essential for recovery.

The paper tracks bacterial evolution and transmission in mice using barcoded E. coli strains, showing rapid selection and migration effects on microbiota composition.

The paper shows that entropy drives disordered proteins through Gram-positive bacterial cell walls, using a physical model and experimental validation.

The paper presents a framework for accurate bacterial growth measurements, revealing effects of culturing conditions, initial cell density, and glycerol on growth rates and fitness.

This study shows that intracellular density in fission yeast changes during the cell cycle due to volume growth modulation, with density decreasing in G2, increasing in mitosis, and dropping at cell birth.

This study evolves Escherichia coli in high osmolarity environments and finds that adaptation strategies vary by osmolyte, with specific mutations improving fitness in certain conditions.

This study develops a high-throughput method to cultivate diverse, stable fecal-derived microbial communities in vitro, demonstrating their utility for modeling the intestinal microbiota and predicting in vivo responses to antibiotics.

SiCTeC enables rapid, precise temperature shifts for single-cell imaging, revealing cellular responses to temperature changes in E. coli.

This paper develops a solvatochromic dye conjugate for rapid, sensitive detection of Mycobacterium tuberculosis in minutes.

The paper quantifies surface area to volume ratio dynamics in bacteria under environmental changes and develops a model linking these dynamics to gene expression and growth control.

The paper investigates how gut microbiota recovers after antibiotics, showing diet and environmental factors influence resilience and recovery patterns.

This paper introduces expansion microscopy to distinguish bacterial species and detect phenotypic changes in dense microbial communities.

This study systematically measures mutant phenotypes for genes in Bacteroides thetaiotaomicron to uncover gene functions and improve understanding of gut microbiota physiology.

This study shows that interspecies interactions in a fruit fly gut microbiota modulate pH and antibiotic tolerance, with Lactobacillus plantarum showing rifampin tolerance influenced by Acetobacter species.

The paper shows that fission yeast can accumulate biomass without expanding in volume, leading to supergrowth when volume expansion resumes.

This study shows that left-handed twisting in MreB filaments, influenced by nucleotide and membrane binding, determines filament length and orientation in Caulobacter crescentus.

This study shows that E. coli regulates cell width by modulating RodZ and MreB to control cell-wall insertion patterns.