Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function
W. Xu, C. Billon, H. Li, M. Hayes, K. Yu, M. Losby, C. S. Hampton, C. M. Adeyemi, A. Graves, E. Nasiotis, C. Fu, R. Welch, R. M. Evans, L. Pei, J. K. Walker, , L. Zhang
This study develops two ERR agonists that improve heart failure by enhancing fatty acid metabolism and mitochondrial function in mice.
bioRxiv · Feb 14, 2022 · PreprintPharmacology & Toxicology