The genetic evolution of acral melanoma
M. Wang, S. Fukushima, Y.-S. Sheen…·B. C. Bastian
This study analyzes exome sequencing data from acral melanoma patients to identify distinct genetic evolution patterns compared to sun-exposed melanomas.
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5 papers
Recent·Most cited
M. Wang, S. Fukushima, Y.-S. Sheen…·B. C. Bastian
This study analyzes exome sequencing data from acral melanoma patients to identify distinct genetic evolution patterns compared to sun-exposed melanomas.
R. L. Bowman, R. C. Hennessey, D. A. Tallman…·C. E. Burd
This study compares UVB mutagenesis effects in NRAS- and BRAF-mutant mouse melanoma models, finding BRAF-mutant tumors have more mutations and a stronger UVB mutational signature.
This study identifies 30 driver genes in cutaneous squamous cell carcinoma through meta-analysis of sequencing data, highlighting mutations in NOTCH, p53, Hippo, Ras/MAPK/PI3K, cell-cycle checkpoint, and chromatin remodeling pathways.
A. S. McNeal, R. L. Belote, H. Zeng…·R. L. Judson-Torres
This study identifies microRNA-mediated suppression of AURKB as a mechanism by which BRAFV600E induces reversible mitotic arrest in human melanocytes, contributing to nevus formation.
W. CAO, H. Lee, W. Wu…·T. G. Bivona
The paper identifies epigenetic drivers of esophageal squamous cell carcinoma through multi-omics analysis, revealing hypomethylation patterns and non-canonical WNT signaling activation.