Author

A. Sabbagh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Garcia· 2 shared D. Courtin· 2 shared J. Clain· 2 shared L. Gineau· 2 shared R. Adamou· 2 shared A. Blake· 1 shared A. Burns· 1 shared A. Fricot· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersPhysiology

A. Garcia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Splenic clearance of rigid erythrocytes as an inherited mechanism for splenomegaly and natural resistance to malaria

B. Henry, G. Volle, H. Akpovi, L. Gineau, C. Roussel, P. A. Ndour, F. Tossou, F. Suarez, F. Palstra, A. Fricot, C. Chambrion, J. Solinc, J. Nguyen, M. Gare, F. Aussenac, , P. Buffet

The paper identifies a genetic mechanism in Fulani individuals that enhances splenic clearance of rigid erythrocytes, contributing to splenomegaly and partial malaria resistance.

bioRxiv · Mar 21, 2022Physiology

LILRB1 and LILRB2 expression in peripheral blood immune cells at 18 and 24 months of age in infants born from mothers with placental malaria

C. Dechavanne, O. Nouatin, R. Adamou, S. Edslev, A. Hansen, F. Meurisse, I. Sadissou, E. Gbaguidi, J. Milet, G. Cottrell, L. Gineau, A. Sabbagh, A. Massougbodji, K. Moutairou, E. A. Donadi, , D. Courtin

This study examines LILRB1 and LILRB2 expression in immune cells of infants born to mothers with placental malaria, finding lower non-classical monocytes and higher LILRB2 expression associated with increased malaria susceptibility.

bioRxiv · Oct 26, 2021 · PreprintImmunology

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes

M. Eyres, S. Lanfredini, A. Burns, A. Blake, F. Willenbrock, R. Goldin, D. Hughes, S. Hughes, A. Thapa, D. Valoulis, A. Hubert, Z. D'Costa, A. Sabbagh, A. G. Abraham, C. Blancher, , E. O'Neill

This study identifies TET2-driven 5hmc loss at GATA6 as a mechanism defining PDAC transcriptional subtypes and shows that TET2 stabilization with Metformin and Vitamin C reverses squamous-like tumor features.

bioRxiv · Oct 22, 2020Cancer Biology

Structural evolutionary analysis predicts functional sites in the artemisinin resistance malaria protein K13

R. Coppee, D. Jeffares, A. Sabbagh, J. Clain

The paper identifies conserved regions in the K13 protein of Plasmodium falciparum as potential functional sites using evolutionary and structural analysis.

bioRxiv · Jun 21, 2018 · PreprintEvolutionary Biology