Author

A. Hjelmeland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Burlingame· 1 shared A. Chumakova· 1 shared A. Dhawan· 1 shared A. G. Fletcher· 1 shared A. Gunter· 1 shared A. Moran· 1 shared A. R. A. Anderson· 1 shared A. Sohrabi· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Burlingame

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Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 17, 2022

PKD-1 Signaling Is Required for the Maintenance of CSCs with Epithelial-mesenchymal Plasticity in Pancreatic Neuroendocrine Tumors

Y. Guo, Y. Jiang, J. B. Rose…·B. Ren

This study shows PKD-1 signaling is essential for maintaining CSCs with epithelial-mesenchymal plasticity in pNETs, suggesting it as a therapeutic target.

DOI 10.1101/2022.02.17.480869

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivMar 5, 2021

Fine-tuned repression of Drp1 driven mitochondrial fission primes a slow cycling stem/progenitor-like state towards accelerating neoplastic transformation of keratinocytes

K. Mitra, B. M. Spurlock, D. Parker…·A. Moran

The paper shows that fine-tuned Drp1 repression primes keratinocytes for neoplastic transformation by maintaining a stem/progenitor-like state with elevated stem markers and Cyclin E.

DOI 10.7554/elife.68394

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 12, 2020

Endothelial-secreted Endocan protein acts as a PDGFR alpha ligand and regulates vascularity, radioresistance, and regional phenotype in glioblastoma

S. Bastola, M. S. Pavlyukov, Y. Ghochani…·H. Kornblum

This study identifies Endocan as an endothelial-secreted ligand for PDGFR alpha that promotes GBM vascularity, radioresistance, and phenotypic diversity.

DOI 10.1101/2020.10.12.335091

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCurrent Stem Cell ReportsPeer-reviewedFeb 15, 2019

Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces

J. G. Scott, A. Dhawan, A. Hjelmeland…·A. R. A. Anderson

The paper unifies the cancer stem cell and stochastic models using a continuum model of microenvironmental forces, supported by clonogenic assay results.

DOI 10.1007/s40778-019-0153-0

mechanistic / dynamical modelcancer & tumor microenvironment

𝕏 PostBluesky