MicrobiologybioRxiv
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
G. Shi, A. I. Chiramel, K. K. Lai…·A. A. Compton
This study shows rapalogs like rapamycin increase SARS-CoV-2 infection by reducing antiviral proteins through microautophagy, while ridaforolimus has less effect.
DOI 10.1172/jci160766