Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
T. Li, I. Kang, J. Ye, Z. Hu, J. Gibbs, C. Ye, K. Takeda, I. Kosik, G. Shi, J. Holly, M. Kosikova, Z. Ye, A. A. Compton, L. Martinez-Sobrido, R. Johnson, , J. W. Yewdell
This study shows that SARS-CoV-2 syncytia reduce interferon and antibody effectiveness, explaining the evolution of fusogenic viral variants.
bioRxiv · Dec 12, 2023Microbiology
N. Mak, D. Zhang, X. Li, K. Rahman, S. A. K. Datta, J. Taylor, J. Liu, Z. Shi, N. Temperton, A. T. Irving, A. A. Compton, R. D. Sloan
The paper identifies alternative splicing of IFITM genes in Chinese horseshoe bats, producing two isoforms with differential antiviral activities against influenza and coronaviruses.
bioRxiv · Dec 4, 2023 · PreprintMicrobiology
K. Rahman, S. A. K. Datta, A. H. Beaven, A. A. Jolley, A. J. Sodt, A. A. Compton
This study shows that cholesterol binds to the amphipathic helix of IFITM3, influencing its antiviral activity by affecting membrane rigidity and fusion pore formation.
bioRxiv · Apr 21, 2022Immunology
G. Shi, A. I. Chiramel, K. K. Lai, A. Kenney, T. Li, T. Dempsey, A. Zani, L. Zhang, S. Majdoul, S. Das, P. A. Beare, S. Kar, T. Andresson, S. M. Best, J. S. Yount, A. A. Compton
This study shows rapalogs like rapamycin increase SARS-CoV-2 infection by reducing antiviral proteins through microautophagy, while ridaforolimus has less effect.
bioRxiv · Apr 15, 2021Microbiology
K. Rahman, C. A. Coomer, S. Majdoul, S. Ding, S. Padilla-Parra, A. A. Compton
This study identifies a conserved GxxxG motif in IFITM3 that drives oligomerization and antiviral activity by promoting membrane rigidity.
bioRxiv · May 14, 2020Evolutionary Biology
C. A. Coomer, I. Carlon-Andres, M. Iliopoulou, M. L. Dustin, E. B. Compeer, A. A. Compton, S. Padilla-Parra
This study links host cell glycolytic activity to membrane tension and shows how it affects HIV-1 fusion in single cells.
bioRxiv · Jul 4, 2019Immunology