Cell BiologybioRxiv
Reflux of Endoplasmic Reticulum proteins to the cytosol yields inactivation of tumor suppressors
D. Sicari, R. Pineau, P.-J. Le Reste…·A. Igbaria
The paper identifies a mechanism where ER proteins are refluxed to the cytosol, inactivating tumor suppressors like p53 in glioblastoma cells.