BiochemistrybioRxiv
Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification
S. E. Thomas, A. J. Whitehouse, K. Brown…·V. Mendes
This study identifies new TrmD inhibitors for mycobacterial infections using fragment-based drug discovery, showing activity against multiple mycobacterial species in vitro and in macrophage models.
DOI 10.1093/nar/gkaa539