Author

A. Jacinto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 2 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

M. G. Cabral· 3 shared S. Braga· 3 shared D. P. Saraiva· 2 shared L. Carvalho· 2 shared R. Salvador· 2 shared A. Antunes· 1 shared A. Jacinta-Fernandes· 1 shared A. Kreuchwig· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersImmunology

M. G. Cabral

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Dachsous is a key player in epithelial wound closure by modulating cell shape changes and cytoskeleton dynamics

P. Porfirio-Rodrigues, T. Pereira, A. Jacinto, L. Carvalho

This study identifies Dachsous as essential for epithelial wound closure by modulating cell shape changes and cytoskeleton dynamics in Drosophila embryos.

bioRxiv · Jul 17, 2024Cell Biology

Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causes in vitro and in vivo Inflammation

N. Domingues, J. Gaifem, R. Matthiesen, D. Saraiva, L. Bento, A. Marques, I. Soares, J. Sampaio, C. Klose, M. Surma, M. Almeida, G. Mendes, P. Goncalves, J. Ferreira, R. Gouveia e Melo, , O. V. Vieira

The paper identifies cholesteryl hemiazelate (ChA) as an oxidized lipid that induces inflammation in vitro and in vivo, contributing to atherosclerosis.

bioRxiv · Feb 9, 2023 · PreprintPathology

Determination of HLA-DR level in cytotoxic T lymphocytes: a new validated tool to predict breast cancer response to treatment

D. P. Saraiva, S. Azeredo-Lopes, A. Antunes, R. Salvador, P. Borralho, B. Assis, I. Pereira, Z. Seabra, I. Negreiros, A. Jacinto, S. Braga, M. G. Cabral

This paper validates HLA-DR expression in cytotoxic T lymphocytes as a predictive biomarker for breast cancer response to neoadjuvant chemotherapy and shows its association with progression-free survival.

bioRxiv · Apr 29, 2021 · PreprintImmunology

Circulating Low Density Neutrophils of Breast Cancer Patients are Associated with their Worse Prognosis due to the Impairment of T cell Responses

D. P. Saraiva, B. F. Correia, R. Salvador, N. de Sousa, A. Jacinto, S. Braga, M. G. Cabral

This study shows that low density neutrophils (LDN) in breast cancer patients are linked to worse prognosis due to their immunosuppressive effects on T cell responses.

bioRxiv · Feb 19, 2021 · PreprintImmunology

Differential expression between African-ancestry and White patients diagnosed with Triple-Negative Breast Cancer: EGFR, Myc, Bcl2 and β-Catenin as ancestry-associated markers

A. T. Matias, A. Jacinta-Fernandes, A.-T. Maia, S. Braga, A. Jacinto, M. G. Cabral, P. H. Brito

This study identifies ancestry-associated gene and protein expression differences in Triple-Negative Breast Cancer between African-ancestry and White patients, highlighting EGFR, Myc, Bcl2, and β-Catenin as potential markers.

bioRxiv · Nov 13, 2020 · PreprintCancer Biology

Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing

S. Ponte, L. Carvalho, M. Gagliardi, I. Campos, P. J. Oliveira, A. Jacinto

This study shows that Drp1-mediated mitochondrial fission is essential for calcium and F-actin dynamics during wound healing in Drosophila embryos.

bioRxiv · Aug 6, 2019Cell Biology

The Aryl Hydrocarbon Receptor senses the Henna pigment Lawsone and mediates Yin-Yang effects on skin homeostasis

L. Lozza, P. Moura-Alves, T. Domaszewska, C. Lage Crespo, I. Streata, A. Kreuchwig, M. Bechtle, M. Klemm, U. Zedler, S. Ungureanu Bogdan, U. Guhlich-Bornhof, A.-B. Koehler, M. Staeber, H.-J. Mollenkopf, R. Hurwitz, , S. H. E. Kaufmann

This study shows that Lawsone, a Henna pigment, activates the AhR receptor in skin cells, with both beneficial and harmful effects depending on the physiological context.

bioRxiv · Nov 4, 2018 · PreprintCell Biology