Author

A. K. Best

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. E. Isakson· 2 shared L. J. DeLalio· 2 shared A. Islam· 1 shared A. M. Miller· 1 shared A. S. Keller· 1 shared A. S. Padilha· 1 shared C. A. Ruddiman· 1 shared C. Lechauve· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

B. E. Isakson

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2 papers

Recent·Most cited

PhysiologybioRxivFeb 12, 2021

Endothelial alpha globin is a nitrite reductase

T. C. S. Keller, A. S. Keller, G. B. Broseghini-Filho…·B. E. Isakson

This study shows endothelial alpha globin functions as a nitrite reductase to mediate hypoxia-induced vasodilation in resistance arteries.

DOI 10.1038/s41467-022-34154-3

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivSep 6, 2019

Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium

Y. Yang, L. J. Delalio, A. K. Best…·S. R. Johnstone

This study shows that endothelial pannexin 1 channels regulate inflammation by controlling intracellular calcium, which in turn affects IL-1β production and release.

DOI 10.4049/jimmunol.1901089

humanbulk RNA-seq

𝕏 PostBluesky