A. Islam

Transarterial Embolization Using a Liquid Embolic Enhances Tumor Necrosis to Enable Improved Efficacy Compared with a Particle Embolic in a Translational Rat Model of Hepatocellular Carcinoma

This study compares liquid embolic (LE) and particle embolic (PE) in transarterial embolization (TAE) for hepatocellular carcinoma (HCC) in rats, finding LE induces greater tumor necrosis and improved treatment response.

Site-specific acetylation of polynucleotide kinase 3-phosphatase (PNKP) regulates its distinct role in DNA repair pathways

This study shows that acetylation of PNKP at K142 and K226 regulates its distinct roles in DNA repair pathways, with K142 involved in BER/SSBR and K226 in DSBR.

Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells

This study identifies 4-dmH, a water-soluble heliomycin derivative, as more effective than parental heliomycin in oral cancer by targeting the tNOX-SIRT1 axis and inducing apoptosis.

Interaction of Fungal lipase with potential phytotherapeutics

This study investigates the interaction of thymol, carvacrol, and linalool with fungal lipase and HSA using spectroscopy and docking, finding thymol most effective in disrupting lipase structure.

Human genetic variations reveal Chromosomal Instability aiding Variants (CIVa) in kinetochore-microtubule associated proteins

The paper identifies Chromosomal Instability aiding Variants (CIVa) in kinetochore-microtubule proteins by analyzing LoF variants in chromosome segregation genes across 150,000 humans, revealing harmful and resilient variants.

Nipah virus detection at bat roosts following spillover events in Bangladesh, 2012-2019

The paper investigates Nipah virus shedding in bat roosts near human cases in Bangladesh, finding that viral RNA can be detected up to 52 days post-exposure, supporting targeted sampling for better viral ecology understanding.

Endothelial alpha globin is a nitrite reductase

This study shows endothelial alpha globin functions as a nitrite reductase to mediate hypoxia-induced vasodilation in resistance arteries.

The ecology of Nipah virus in Bangladesh: a nexus of land use change and opportunistic feeding behavior in bats

The paper examines factors driving Nipah virus spillover in Bangladesh, finding winter temperature explains 53% of annual spillover variation and linking land use changes to bat behavior and viral transmission risk.

Abuse liability, antinociceptive, and discriminative stimulus properties of IBNtxA

This study evaluates the analgesic, rewarding, and discriminative stimulus properties of IBNtxA, finding it produces potent antinociception with low abuse liability due to κ agonist effects.

Comparative analysis of chemically and biologically synthesized iron oxide nanoparticles against Leishmania tropica

This study compares the antileishmanial effects of chemically and plant-synthesized iron oxide nanoparticles against Leishmania tropica, showing higher efficacy of plant-synthesized nanoparticles.