PhysiologybioRxiv
Polarized localization of phosphatidylserine in endothelium regulates Kir2.1
C. A. Ruddiman, R. Peckham, M. A. Luse…·B. E. Isakson
The paper shows phosphatidylserine (PS) localizes to myoendothelial junctions (MEJs) in endothelium, inhibiting PIP2-mediated Kir2.1 activation to regulate vascular diameter.
DOI 10.1172/jci.insight.165715