Author

A. L. Bain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. K. Khanna· 3 shared A. Burgess· 2 shared B. Rashidieh· 2 shared D. Sinha· 2 shared J. Finnie· 2 shared M. Kalimutho· 2 shared P. H. G. Duijf· 2 shared B. Shohayeb· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

K. K. Khanna

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Author profile →

3 papers

Recent·Most cited

Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice

B. Rashidieh, A. L. Bain, S. M. Tria, S. Sharma, C. A. Stewart, J. L. Simmons, P. M. Apaja, P. H. G. Duijf, J. Finnie, K. K. Khanna

This study shows that overexpression of B-Crystallin in mice promotes tumorigenesis and metastasis by enhancing cell survival and inhibiting apoptosis.

bioRxiv · Jul 27, 2022Cancer Biology

Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis

B. Rashidieh, B. Shohayeb, A. L. Bain, P. R. J. Fortuna, D. Sinha, A. Burgess, R. Mills, R. C. Adams, J. A. Lopez, P. Blumbergs, J. Finnie, M. Kalimutho, M. Piper, J. E. Hudson, D. Ng, K. k. Khanna

This study shows that Cep55 regulates PI3K/Akt signaling, essential for neocortical development and ciliogenesis, using mouse models and human organoids.

bioRxiv · Jan 8, 2021 · PreprintCell Biology

Cep55 overexpression promotes genomic instability and tumorigenesis in mice

D. Sinha, P. Nag, D. Nanayakkara, P. H. G. Duijf, A. Burgess, P. Raninga, V. A. J. Smits, A. L. Bain, G. N. Subramanian, M. Wall, J. W. Finnie, M. Kalimutho, K. K. Khanna

This study shows that Cep55 overexpression causes genomic instability and tumorigenesis in mice by promoting mitotic errors and disrupting DNA repair mechanisms.

bioRxiv · Sep 24, 2019Cancer Biology