Author

A. Leith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:software / tool· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Budelsky· 1 shared A. Hochheimer· 1 shared A. Ragavendran· 1 shared B. Bennett· 1 shared B. Liu· 1 shared B. Martin· 1 shared C. C. Suiter· 1 shared C. Lee· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperPhysiology

A. Budelsky

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Precise genomic deletions using paired prime editing

J. Choi, W. Chen, C. C. Suiter, C. Lee, F. M. Chardon, W. Yang, A. Leith, R. M. Daza, B. Martin, J. Shendure

This paper introduces PRIME-Del, a prime editing method for precise genomic deletions, showing higher precision than CRISPR/Cas9 and enabling deletions with non-PAM junctions.

bioRxiv · Dec 30, 2020Bioengineering

NMRdock: Lightweight and Modular NMR Processing

K. W. East, A. Leith, A. Ragavendran, F. Delaglio, G. P. Lisi

NMRdock provides a containerized solution for NMR data processing to reduce complexity and improve accessibility for newcomers and maintainability of software.

bioRxiv · Jun 25, 2019 · PreprintBiophysics

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide are Potent TMEM16A Antagonists that Fully Bronchodilate Airways

K. Miner, K. Labitzke, B. Liu, P. Wang, K. Henckels, K. Gaida, R. Elliott, J. J. Chen, L. Liu, A. Leith, E. Trueblood, K. Hensley, X.-Z. Xia, O. Homann, B. Bennett, , J. K. Sullivan

This paper identifies niclosamide and nitazoxanide as potent TMEM16A antagonists that fully bronchodilate airways, offering new treatment options for severe asthma and COPD.

bioRxiv · Nov 14, 2018Physiology