Z.-M. Zheng

The paper designs long-acting GLP-1 receptor agonists using structural biology to prevent DPP-4 degradation while maintaining receptor binding, achieving hypoglycemic effects lasting over 24 hours.

This study identifies ORF57's role in regulating KSHV RNA splicing, revealing its impact on viral gene expression and immune evasion during lytic infection.

This study shows DDX6 in P-bodies is essential for stress granule assembly, with its helicase activity suppressing stress granule formation in normal cells.

The paper challenges the claim that HPV16 circular RNA circE7 drives cell transformation, showing its low abundance and attributing observed effects to off-target siRNA effects on linear E7 mRNAs.

The paper identifies that HPV oncogenes are expressed from a single integration site in cervical cancer cell lines, revealing mechanisms of viral-host fusion transcript production and their impact on cell growth.

This paper shows that papillomavirus can be transmitted through blood and cause infections in animal models, suggesting blood transfusion as a potential route for HPV infection and cancer in humans.