S. Ratnayake

A transposable element insertion in IAA16 disrupts splicing and causes dicamba resistance in Bassia scoparia

This study identifies a transposable element insertion in AUX/IAA16 that disrupts splicing and causes dicamba resistance in kochia, with implications for herbicide resistance management.

TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers

This study shows TRAIL treatment of TNBC cells activates the NFKB2 pathway, leading to cytokine production that enhances neutrophil chemotaxis and immune suppression.

The ESCRT protein CHMP5 promotes T cell leukemia by controlling BRD4-p300-dependent transcription

This paper identifies CHMP5 as a nuclear factor that promotes T cell leukemia by enhancing BRD4-p300-dependent transcription at enhancers and super-enhancers.

Gene regulatory network inference in soybean upon infection by Phytophthora sojae

This study uses transcriptome and deep learning to infer gene regulatory networks in soybean responding to Phytophthora sojae infection, identifying key transcription factors involved in defense.

Flotillin-2 regulates EGFR activation, degradation, and cancer growth

This study shows that Flotillin-2 negatively regulates EGFR activation, ubiquitination, trafficking, and degradation, thereby suppressing cancer growth.

Whole Organism Profiling of the Timp Gene Family

The paper analyzes Timp gene expression across healthy tissues using single-cell RNA sequencing to identify cell-type-specific patterns and expand on these findings with RNA in-situ hybridization.