Cell BiologybioRxiv
Selective targeting of non-centrosomal AURKA functions through use of a targeted protein degradation tool
R. K. Wang, C. Ascanelli, A. M. Abdelbaki…·C. Lindon
This study characterizes a PROTAC-based degrader of AURKA, showing differential targeting of subcellular AURKA pools and distinct phenotypic effects compared to traditional inhibitors.
DOI 10.1038/s42003-021-02158-2